MEDICALLY REVIEWED BY ELIZABETH A. SWICK, MS, RDN

What is Bonolive®? The Groundbreaking Science behind this Game-Changing Women's Health Supplement

What is Bonolive®? The Groundbreaking Science behind this Game-Changing Women's Health Supplement

Osteo Plus: Unleashing the Power of Bonolive®  

Maintaining optimal bone health is crucial, especially for post-menopausal women who are at higher risk for osteoporosis and bone fractures. Calcium supplementation has long been recommended to support bone health, but recent scientific advancements have led to the development of a groundbreaking bone health supplement called Bonolive®. Osteo Plus, developed by Innerthera, is a unique formulation that combines the goodness of calcium with the power of Bonolive®, a natural olive extract. In this article, we will explore the science behind Bonolive® and how it can unleash the power of bone health, promoting strong, healthy joints. So, if you are interested in maximizing your bone health and preventing osteoporosis, keep reading to learn more about Bonolive® and its benefits for you.

Understanding the Importance of Bone Health

Understanding the importance of bone health is crucial for maintaining overall well-being. Our bones serve as the framework that supports our bodies and allows us to move freely. Strong and healthy bones are essential for proper posture, balance, and mobility, especially as we age. Neglecting bone health can lead to various complications, including osteoporosis and an increased risk of fractures. This is particularly significant for post-menopausal women, as hormonal changes can accelerate bone loss.

Calcium supplementation has long been recommended to support bone health, as calcium is a vital mineral for building and maintaining bone strength. However, recent scientific advancements have brought forth a new innovative supplement called Osteo Plus, formulated with Bonolive®. 

The Science Behind Bonolive®: A Breakthrough in Bone Health

Bonolive® is not just any ordinary bone health supplement. It is a product of groundbreaking scientific research that has revolutionized the way we approach bone health. Developed by a team of skilled scientists, Bonolive® is a patented olive leaf extract derived from the world’s largest olive region of Jaén in Spain, and developed to support women’s health during menopause.

At the core of this revolutionary supplement is a key component called oleurpein, the most abundant polyphenol found in olive leaves. Its action can improve bone metabolism, inflammation, and oxidative stress. It works by stimulating the activity of osteoblasts, the cells responsible for building new bone tissue, while simultaneously increasing osteocalcin levels, the cells that break down bone.

What sets Bonolive® apart is its ability to increase bone mineral density, improve bone strength, and promote bone formation, all without the common side effects associated with traditional supplementation. This remarkable supplement truly unlocks the power of bone health and offers a promising solution for those seeking to support and strengthen their bones.

In the next section, we will delve deeper into the specific scientific studies and clinical trials that have substantiated the effectiveness of Bonolive®, giving you a comprehensive understanding of why Osteo Plus is a game-changer in the realm of bone health. 

Clinical Studies and Evidence Supporting the Effectiveness of Bonolive®

Bonolive®’s game-changing approach to bone health is not just a result of marketing hype. Its effectiveness is backed by a series of scientific studies and rigorous clinical trials that have yielded compelling results.

Numerous studies have demonstrated Bonolive®’s ability to increase bone mineral density and improve bone strength. In one randomized controlled trial involving postmenopausal women, those who took Bonolive® experienced a significant increase in bone mineral density compared to the control group.

Furthermore, Bonolive® has shown promising results in promoting bone formation. A separate study found that individuals who took Bonolive® had increased levels of osteoblast activity, leading to enhanced bone remodeling.

As for Bioavailability, A third clinical study was conducted to investigate the oral bioavailability of Bonolive® in postmenopausal women compared to premenopausal women. Results showed the consumption of 250 mg of Bonolive®, significantly increased metabolite concentrations in plasma and urine, mainly in the form of sulphate and glucuronide conjugates. Fifteen metabolites were detected in plasma, with hydroxytyrosol glucuronide as the most abundantone. This olive-leaf-derived-metabolite appeared in plasma 30 min after Bonolive® intake and remained detectable for up to 8 hours as shown in the following graph:

One of the most remarkable aspects of Bonolive® is its lack of common side effects associated with other supplements. This has been consistently demonstrated in multiple studies, making Bonolive® a safe and well-tolerated option for improving bone health.

The scientific evidence supporting Bonolive®’s effectiveness makes it an exciting breakthrough in the field of bone health. In the next section, we will explore the specific mechanisms by which Bonolive® works to deliver impressive results for those taking Osteo Plus.  

How Bonolive® Works: Mode of Action

Osteoblast activation

In women, the decrease in estrogen associated with menopause, accelerates the net bone loss, leading to a higher risk of developing osteoporosis.

 Oleuropein, one of the key components of Bonolive®, promotes bone formation by enhancing differentiation of stem cells into osteoblasts. Thus, Bonolive® helps to protect the healthy balance of bone metabolism that weakens with age(figure2).

Cartilage regeneration

Bonolive® also affects joint health. Oleuropein treatment leads to a downregulation of Cx43 activity, leading to a pro-regenerative environment in the joints.

Additionally, oleuropein can reduce levels of inflammation and cartilage degradation biomarkers (such as PGE-2 and collagen-II) which can be involved in the process of osteoarthritis.

The regenerative effect on the bone cartilage is accomplished through inhibition of NF-κB and MAPK signaling pathways. This leads to a reduced risk of osteoarthritis, cartilage degeneration, joint inflammation and thus muscle weakness.

Lipid storage reduction

Finally, since osteoblasts and adipocytes are derived from a common MSC progenitor, stimulation of osteoblast formation by oleuropein, also affects bone marrow adipocyte formation. This translates into a reduction of lipid storage and an improvement of the lipid profile.

Benefits of Incorporating Bonolive® Into Your Daily Routine

Incorporating Bonolive® into your daily routine can provide a multitude of benefits for your bone health. By stimulating osteoblast activity , Bonolive® promotes bone formation and helps maintain optimal bone density. This can be especially beneficial for individuals at risk of osteoporosis or those looking to improve their bone strength.

The antioxidant properties of Bonolive® also contribute to its benefits. By neutralizing free radicals, this supplement helps protect bone cells from oxidative damage, reducing the risk of bone loss and deterioration. Additionally, Bonolive®'s ability to support factors involved in bone remodeling, such as reducing inflammation and promoting collagen synthesis, further enhances its effectiveness in maintaining healthy bones.

Frequently asked Questions about Bonolive®

As the awareness of Bonolive® grows, it is natural that questions arise about this groundbreaking bone health supplement. To help address questions that you may have, we have compiled a list of frequently asked questions about Bonolive®.

Q1. What is the recommended dosage of Bonolive®?

The recommended dosage of Bonolive® varies depending on factors such as age, gender, and overall bone health. It is best to consult with a healthcare professional to determine the appropriate dosage for your specific needs. InnerThera's Osteo Plus delivers 250 mg of Bonolive® for a potent 40% concentration of oleuropein compounds from Mediterranean olive leaves.

Q2. How should I incorporate Bonolive® into my daily routine?

Osteo Plus Bonolive® is available in capsules, making it convenient to take. It is usually recommended to take Bonolive® with a meal to enhance absorption. Follow the instructions on the packaging or consult with a healthcare professional for specific guidance on incorporating Bonolive® into your daily routine.

Q3. Are there any side effects associated with Bonolive®?

Bonolive® is generally well-tolerated and does not have any known serious side effects. However, as with any dietary supplement, some individuals may experience mild reactions such as stomach discomfort or allergies. If you experience any adverse effects, discontinue use and consult with a healthcare professional.

Q4. Can Bonolive® be taken alongside other medications or supplements?

While Bonolive® is considered safe for most individuals, it is important to inform your healthcare professional about any medications or supplements you are currently taking. They can assess the potential interactions and provide guidance on the appropriate timing and dosage of Bonolive® in relation to other medications or supplements. 

Embracing the Power of Bonolive® for Optimal Bone Health

In conclusion, Bonolive® offers a groundbreaking solution to support optimal bone health. Through its natural ingredients and innovative formulation, Bonolive® has garnered attention as a game-changing bone health supplement. We have addressed the frequently asked questions about Bonolive®, providing you with important information about dosage, incorporation into your daily routine, possible side effects, and potential interactions with other medications or supplements.

Are you ready to take the next step in optimizing your bone health? Learn more about Osteo Plus NOW!!